APO E Genetic Test - a marker for Alzheimer's

Ritesh Bawri

Jan 15, 2024 — 2 min read

BreatheAgain

Apoliproprotein E (APO E) is a protein that is involved in the use of fat as a source of energy in your body.

It has also been linked to the risk of Alzheimer's disease in human beings. Let us find out why.

In the last century, we have both learned about our genes and decoded them. As more information became available, scientists started to look for possible connections between our genes and diseases.

Scientists have found a common link between the onset of Alzhiemer's and APO E. The link is not causal. APO E is not causing Alziemer's. Instead, it seems that those who get the disease also have this gene.

So you can use APO E as a marker to evaluate your risk for Alzhiemer's.

About 25% of human beings have one copy of APO E, and between 2 and 3 percent have two copies.

Those who do seem to have a higher risk of developing Alzheimer's disease than others.

There are others. ABCA7, CLU, and CRU, for example. All of them have been linked to pathways that ultimately cause the disease.

So what should you do?

In the past, if someone in your family has developed conditions that involve mental faculties, it increases the risk of you inheriting the same.

In such cases, it may be useful for you to get yourself tested. Early detection helps to take preventive action.

Many diseases that involve the brain are progressive in nature. Time makes it worse. So the earlier you find out, the better it is for you.

While there is no known cure, there are several things you can do to slow down the progression. Medicines have been shown to be effective in slowing things down.

Focusing on sleep, nutrition, and exercise will always prove to be beneficial.

Reach out to me on twitter @rbawri Instagram @riteshbawriofficial and YouTube at www.youtube.com/breatheagain

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